Title:Unraveling the stability of plasma proteins upon interaction of synthesized uridine products: biophysical and molecular dynamics approach
DOI:10.1080/07391102.2019.1620127
ligand name:5-CM-MU
ligand smiles:COP(=O)(Cl)OC[C@H]1OC(N2C=CC(=O)NC2=O)[C@](C)(O)[C@@H]1O
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:

#Binding and thermodynamic parameters#
parameter;285nm;
pH;
T;298;
KSV;
kq;
n;0.662;
K;
Ka;
Kb;1.95*10^4;
ΔH;
ΔS;
ΔG;-23.8070;
Kd;


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;

#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;

#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;

#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;



#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;

#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





