Title:Barbiturate squaraine dyes as fluorescent probes for serum albumins detection
DOI:10.1016/j.jphotochem.2020.112710
ligand name:8c
ligand smiles:CCCCCCN1\C(=C\C2=C([O-])\C(=C\C3=[N+](CCCCCC)C4=C(C=CC=C4)C3(C)C)\C2=C2C(=O)N(C(=S)N(C3=CC=CC=C3)C2=O)C2=CC=CC=C2)C(C)(C)C2=C1C=CC=C2
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:both site

#Binding and thermodynamic parameters#
parameter;
pH;
T;
KSV;
kq;
n;
K;
Ka;
Kb;4.44*10^5;
ΔH;
ΔS;
ΔG;
Kd


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;


#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;




#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;


#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





