Title:Antidepressant drug-protein interactions studied by spectroscopic methods based on fluorescent carbon quantum dots.
DOI:10.1016/j.heliyon.2019.e01631
ligand name:amitryptiline hydrochloride 
ligand smiles:CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl  
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:

#Binding and thermodynamic parameters#
parameter;
pH;7.6;
T;300;
KSV;10.02*10^4;
kq;
n;1.089;
K;
Ka;
Kb;10.9*10^4;
ΔH;
ΔS;
ΔG;
Kd;


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;


#UV-vis absorption spectroscopy#
parameter;
pH;7.6;
T;300;
n;
K;
Ka;
Kb;0.64*10^4;
ΔH;
ΔS;
ΔG;
Kd;


#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;




#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;


#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





