Title:Influence of piracetam on gliclazide-glycated human serum albumin interaction. A spectrofluorometric study
DOI:10.3390/molecules24010111
ligand name:GLZ
ligand smiles:CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:Sudlow's sites II(subdomain IIA)

#Binding and thermodynamic parameters#
parameter;
pH;
T;310;
KSV;10.42*10^3;
kq;1.68*10^12;
n;1.05;
K;
Ka;4.21*10^4;
Kb;
ΔH;
ΔS;
ΔG;
Kd


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;


#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;




#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;


#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





