Title:Cyclometalated ruthenium(II) complexes with 3-acetyl-2[H]-chromene-2-one derived CNS chelating ligand systems: synthesis, x-ray characterization and biological evaluation
DOI:10.1039/c7nj02877f
ligand name:H2L1
ligand smiles:C\C(=N/NC(N)=S)C1=CC2=C(OC1=O)C=CC=C2
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:

#Binding and thermodynamic parameters#
parameter;290;
pH;7.2;
T;293;
KSV;0.955*10^4;
kq;0.955*10^12;
n;0.9213;
K;
Ka;
Kb;4.130*10^3;
ΔH;
ΔS;
ΔG;
Kd;


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;

#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;

#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;

#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;



#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;

#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





