Title:Interaction between Human Serum Albumin and antidiabetic compounds and its influence on the O2(1Δg)-mediated degradation of the protein
DOI:10.1016/j.jphotobiol.2014.10.019
ligand name:Gliclazide
ligand smiles:CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:site II

#Binding and thermodynamic parameters#
parameter;
pH;
T;285;292;299;308;
KSV;
kq;
n;
K;
Ka;
Kb;1.15*10^4;1.02*10^4;1.28*10^4;1.03*10^4;
ΔH;
ΔS;
ΔG;
Kd;


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;


#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;




#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;


#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





