Title:Structure-affinity relationship of flavones on binding to serum albumins: effect of hydroxyl groups on ring A
DOI:10.1002/mnfr.200900454
ligand name:7-Hydroxyflavone
ligand smiles:C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)O  
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:site I and site II

#Binding and thermodynamic parameters#
parameter;
pH;
T;300.15;
KSV;3.82*10^5;
kq;
n;1.22;
K;
Ka;3.55*10^6;
Kb;
ΔH;
ΔS;
ΔG;
Kd


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;


#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;




#FRET from Steady State Measurements#
parameter;
pH;
T;
J;0.58*10^-14;
E;
R0;3.29;
r;
EFRET;
F0;
F;


#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





