Title:Synthesis of 2-(4-methylphenyl)-3-(N-acetyl)-5-(2-hydroxyphenyl)-1,3,4-oxodiazoline and its interaction with HSA
DOI:None
ligand name:
ligand smiles:CC(=O)N1N=C(C2=CC=CC=C2O)OC1C1=CC=C(C)C=C1
key residue(hbond):
key residue(hydrophobic):
PDB ID:
Binding Area:

#Binding and thermodynamic parameters#
parameter;
pH;
T;293;301;309;
KSV;
kq;
n;1.06;1.01;0.72;
K;
Ka;
Kb;1.28*10^6;5.08*10^5;4.58*10^3;
ΔH;
ΔS;
ΔG;
Kd;


#ITC#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Cp;
Kd;

#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;

#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;

#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;



#FRET from Steady State Measurements#
parameter;
pH;
T;293;
J;
E;
R0;
r;1.31;
EFRET;
F0;
F;

#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





