Title:Comparative binding character of two general anaesthetics for sites on human serum albumin
DOI:10.1042/bj20031652
ligand name:Propofol
ligand smiles:CC(C)C1=C(C(=CC=C1)C(C)C)O
key residue(hbond):Leu430 d
key residue(hydrophobic):
PDB ID:
Binding Area:subdomain IIIA d

#Binding and thermodynamic parameters#
parameter;
pH;
T;
KSV;
kq;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#ITC#
parameter;
pH;
T;293;
n;1.7;
K;
Ka;
Kb;15280;
ΔH;-21.7526;
ΔS;5.8576;
ΔG;
Cp;
Kd;65;


#UV-vis absorption spectroscopy#
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#other_method#
method;
parameter;
pH;
T;
n;
K;
Ka;
Kb;
ΔH;
ΔS;
ΔG;
Kd;


#Kinetic Parameters Describing Michaelis–Menten Constant#
HSA/Ligand;RA (%);Vmax;Km;kcat;kcat/Km;




#FRET from Steady State Measurements#
parameter;
pH;
T;
J;
E;
R0;
r;
EFRET;
F0;
F;


#Changes in the ASA(Å2) Values of the Interacting Residues of HSA and ligand Complex
residues;ASA(Å2) of HSA;ASA(Å2)of com;ΔASA(Å2)





